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Sehyun Shin
Name
Sehyun Shin | Professor
Tel
+82-2-3290-3377
Fax
+82-2-921-3859
E-mail
lexerdshin@korea.ac.kr
address
314, School of Mechanical Engineering, Korea University, Anamdong, 5-Ga, Sungbuk-Gu, Seoul, Korea, 136-713
Education
1987 B.S. Department of Mechanical Engineering, Seoul National University, Seoul, Korea
1989 M.S. Department of Mechaniacl Engineering, Seoul National University, Seoul, Korea
1993 Ph.D Biofluid School of Mechanical engineering, Drexel University, Philadelphia, USA
Lab.
Bio-Fluid System Lab.
RBC (Red blood cell) aggregation
Red blood cells (RBCs) in our body have a tendency to aggregate like coin stacks. It is called RBC aggregation. If RBCs aggregate too much (hyper-aggregation), the blood viscosity increases. It results in high resistance in blood flow and hypertension. Therefore we developed the RBC aggregometer to try to prevent possible diseases induced by abnormal RBC aggregation.
  • Hemorheology
  • Early diagnosis
  • Cardiovascular diseases
  • Blood viscosity
RBC (Red blood cell) deformability
Red blood cells (RBCs) cannot go through narrow blood vessels without RBC deformation. If RBC deformability decreases, RBCs become solid, which leads to high resistance in blood flow. Finally, it causes diseases such as hypertension and arteriosclerosis. We developed the RBC ektacytometer to estimate RBC deformability. As we apply shear stress on RBCs in microchannel, RBCs deform. Then, we can get the diffraction image from CCD camera, and measure RBC deformability using computer analysis program.
  • Hemorheology
  • Early diagnosis
  • Cardiovascular diseases
SSAW (Standing surface acoustic wave)
Piezo material is a reversible material that can convert the type of energy between electricity and mechanical energy. Using this piezo material we can generate SAW (surface acoustic wave). If we set two IDTs (inter digitized transducers) in parallel direction, and give electric energy to the IDTs, two SAW will be generated and by these two SAWs it will form a SSAW (standing surface acoustic wave). The particle that passes through the SSAW area will experience acoustic force depending by its size, density, and compressibility. By this phenomenon, we can separate various type of particles. We are studying separation of red blood cells, and white blood cells and also plasma from blood.
  • Standing surface acoustic wave
  • Cell (Particle) separation
  • Plasma extraction